Michael A Brodney Selected Research

PF-06751979

1/2019

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of PF-06751979, a Potent and Selective Oral BACE1 Inhibitor: Results from Phase I Studies in Healthy Adults and Healthy Older Subjects.

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Michael A Brodney Research Topics

Disease

14	Alzheimer Disease (Alzheimer's Disease) 07/2019 - 05/2011
1	Neuroinflammatory Diseases 12/2018
1	Hypopigmentation (Hypomelanosis) 01/2018
1	Toxic Optic Neuropathy 10/2016
1	Schizophrenia (Dementia Praecox) 01/2016
1	Nervous System Diseases (Neurological Disorders) 09/2013
1	Cognitive Dysfunction 11/2012
1	Psychotic Disorders (Schizoaffective Disorder) 03/2011

Drug/Important Bio-Agent (IBA)

9	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 07/2019 - 05/2011
6	Amyloid (Amyloid Fibrils)IBA 07/2019 - 08/2012
3	Pharmaceutical PreparationsIBA 01/2018 - 11/2012
2	EnzymesIBA 07/2019 - 01/2018
2	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2018
2	Aspartic Acid ProteasesIBA 01/2019 - 01/2018
2	Cathepsin DIBA 01/2018 - 10/2016
1	Peptides (Polypeptides)IBA 01/2019
1	PF-06751979IBA 01/2019
1	EndocannabinoidsIBA 12/2018
1	CarbamatesIBA 12/2018
1	Monoacylglycerol LipasesIBA 12/2018
1	Cholinergic Agents (Cholinergics)IBA 01/2016
1	5-HT4 Serotonin ReceptorsIBA 09/2013
1	Serotonin (5 Hydroxytryptamine)IBA 09/2013
1	azasteneIBA 09/2013
1	tetrahydrofuranIBA 09/2013
1	Acetylcholine (Acetylcholine Chloride)FDA Link 11/2012
1	DiamideIBA 05/2011
1	ImidazolesIBA 05/2011
1	metabotropic glutamate receptor 2IBA 03/2011
1	Methamphetamine (Desoxyn)FDA LinkGeneric 03/2011
1	Mescaline (Peyote)IBA 03/2011